Pharmacokinetics of therapeutic monoclonal antibodies used in oncology.

نویسندگان

Dominique Levêque

Sandra Wisniewski

François Jehl

چکیده

This review presents the clinical pharmacokinetics of the marketed therapeutic monoclonal antibodies used in oncology. Aspects regarding absorption, tissue distribution, elimination as well as factors influencing pharmacokinetics, pharmacodynamics and kinetic interactions are also discussed.

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